The evaluation of proliferation ability of cardiomyocytes in heart failure

The proliferation ability of cardiomyocytes is always under a controversial situation, especially some stress condition such as heart failure disease and external damages. Heat (HF) complex clinical syndrome that results from left ventricular myocardial dysfunction contributes to dyspnea, fatigue fluid retention. related the cell cycles lot cell-cycle genes are involved in evaluation cardiomyocytes. RNA-seq quite common technique evaluate transcription expression pattern many studies. Here our article we analyzed existing dataset mRNA level several which can be indicators activity cycles. We found cyclin D2 cycle activator upregulated dilated cardiomyopathy (DCM) disease, indicating may higher DCM heart. throw light on research adult